small actıvatıon rna TOOLS

This tool scans the provided DNA promoter sequence to design optimal saRNA (small activating RNA) candidates for gene activation. It uses thermodynamic calculations (Δ G) and Reynolds rules to rank candidates based on their stability and asymmetry using a scientific scoring system. Additionally, it visualizes the duplex structure formed by the Sense (passenger) and Antisense (guide) strands, allowing you to copy them for synthesis. 

This tool generates saRNA candidates in bulk from your DNA sequence and provides an advanced selection and comparison system to manage the best candidates. You can select specific candidates to add to the bottom "Dock" panel, then view and copy them as a consolidated table for export. Additionally, each result card features a duplex visualization showing the hybrid structure of the Sense and Guide strands. 

This tool is a practical converter that instantly transforms a single input DNA promoter sequence into Sense (Passenger) and Antisense (Guide) RNA strands. It visualizes the duplex structure showing how the strands align and automatically reverses the Guide strand into the correct 5' → 3' orientation required for synthesis ordering. It allows you to copy all generated data in a formatted manner with a single click.