orcSONAR predicts saRNA off-target activity in a cell-type-specific way, moving beyond sequence-similarity (BLAST) methods. It integrates 24 genomic, epigenomic, and structural data sources across a 7-stage pipeline into a single per-target risk score.

vuRNA is a hybrid RNA therapeutic concept that combines two mechanisms in a single molecule: the small activating RNA (saRNA) principle, which re-activates silenced tumor-suppressor genes, and miRNA sequestration, which neutralizes over-expressed oncogenic signals. In one molecule, it aims to perform the work that would normally require two separate treatments. 

orcECHO is a next-generation, saRNA-based therapeutic concept designed to drive target genes into controlled hyper-activation — pushing their output beyond the ceiling of conventional activation strategies. The underlying approach is held confidential while the concept is in early development.